Southern Cal at Ducks.  Major implications for the postseason including, perhaps, the Dec 6 game in Indy.  

@big-ryan yep. That’s the headliner

I would add East Carolina vs UTSA to the list - its close to a pickem game, and if ECU falls it would make the AAC championship picture more clear (winner of that makes playoffs). Right now Tulane is in due to the tiebreakers (being ranked in CFP is one), but that conference has a logjam (UNT, Navy, ECU all have 1 conference loss). Its at UTSA, who hasnt lost a home game in 2 seasons. Good chance we see an upset here

I think Mizzou will win, but Im hoping OU pulls out. OU is (IMO) the worst of the teams currently "in" the playoffs, and the team thats knocking on the door (Utah) has been heating up. Utah is also very highly regarded by metrics. Give me a SEC team to humiliate in primetime over a sneaky good Big 12 team anyday

Another game to watch thats semi-relevant to the playoffs, is Kentucky vs Vanderbilt. Kentucky has been playing really well the past couple of weeks with their new QB, good chance for an upset which would knock Vandy out of the at large race

@hoosierdaddy good additions

Ohio State's two, all-world, receivers probably won't play tomorrow verses Rutgers in Columbus. It will be interesting to see how far of a drop-off there is with OSU's passing attack with them missing. 

BYU at Cincinnati is potentially problematic for the Cougars. Michigan at Maryland should be fun. Tennessee at Florida tomorrow evening should provide meaningless entertainment. Of course USC at Oregon might be a game.